Hacks Star Megan Stalter Shares Candid Thoughts on Using Ozempic: 'I'd Rather Be 500 Lbs. Than Be S------- All Day'

"How is that hotter than being fat?" the actress asked during a recent podcast appearance

Megan Stalter attends the 30th Annual Critics Choice Awards
Megan Stalter at the Critics Choice Awards in February 2025. Photo:

Frazer Harrison/Getty

Megan Stalter says there is one reason why she has no intention of trying Ozempic, the type 2 diabetes drug that many have also used for weight loss.

While appearing on the March 13 episode of Grindr Presents: Who’s The A-----? with Katya podcast, the Hacks star, 34, spoke about a host of topics with RuPaul's Drag Race alum Katya Zamolodchikova, including sexuality and sex toys, as well as the side effects of the popular injectable.

In a round of the podcast's titular game, Katya, 42, asked Stalter what she thinks about people who "lie about using Ozempic," which prompted the star to respond that she thinks people are fooling themselves if they think they can hide their use of the drug.

"Let's just say the trips to the bathroom would say otherwise, okay? We know if you're on it because you're s------- your pants," she said. "How is that hotter than being fat? That is insane to me. That is crazy."

"I would rather be 500 lbs. than s------- all day. That's so gross," the comedian added.

Meg Stalter on Dressing for Red Carpets: I 'Don't Really Go by the Rules'
Meg Stalter on the red carpet in September 2022. Unique Nicole/WireImage, Evans Vestal Ward/NBC via Getty

Ozempic is an injectable drug approved by the Food and Drug Administration (FDA).

It's just one of many brand names (Wegovy is another popular one) for semaglutide, the active ingredient in all of the hormone based GLP-1 drugs that target the brain to impact satiety.

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While these drugs' intended purpose is to treat diabetes, kidney disease or to help people struggling with obesity, they have also been controversially co-opted as a weight loss drug, per the FDA.

A common early side effect of Ozempic, per the manufacturer's website, can be diarrhea. Constipation, nausea and stomach pain are also listed as other possible side effects.

Reflecting more on using drugs for weight loss, Stalter said, "Unless you have a sickness, then that is something you were born with. But if you're taking a drug on purpose to s--- your brains out, just so you lose 10 pounds, honey, we liked you a little chubbier."

"It's wild," Katya agreed, adding that he was first introduced to the drug when he "heard" that others who used it were reportedly "blowing up the bathrooms."

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